What is injectable PrEP?

It is a new PrEP option that replaces the daily pill with a long-acting injection.

The medication used is cabotegravir (sold under the brand name Apretude®). It works on the same principle as oral PrEP—maintaining a concentration of the drug in the body to block HIV—but its formula allows it to be released very slowly, providing continuous protection. After a start-up phase, the schedule consists of one injection every two months.

What are the advantages of injectable PrEP?

Studies show that injectable PrEP is even more effective than oral PrEP because it eliminates the risk of missed doses, which is the main factor that can reduce the effectiveness of the pills.

People also choose it for several reasons that improve their quality of life:

• Less mental load: No longer having to think about taking a pill every day frees up considerable mental space.
• More spontaneity and discretion: Protection is constant without daily action and with no pill bottles to manage.
• A solution for adherence challenges: It is an ideal option for people with irregular lifestyles (variable work schedules, frequent travel).
• Avoiding gastrointestinal effects: The injection bypasses the digestive system, which is an advantage for those who are sensitive to GI side effects.

Is it the best option for everyone?

Not necessarily. Despite its advantages, it requires a commitment to visit a clinic every two months for injections. Discontinuing the treatment is also more complex than with oral PrEP.

The best approach is to discuss it. Our pharmacists are here to help you choose the treatment that best suits your reality, preferences, and lifestyle.