How do I achieve maximum protection with PrEP?

The answer is simple: by following your treatment rigorously.

The effectiveness of PrEP is not a matter of luck, but of science. Maintaining a sufficient concentration of the medication in your body is the only way to achieve the greater than 99% effectiveness demonstrated in studies.


What does that mean in practice?

It means following the protocol that was prescribed for you, without compromise.

  • For daily oral PrEP: Take one pill, every day, ideally at the same time. Integrate it into a routine (waking up, meals, bedtime) to make it automatic. Maximum protection is reached 7 days after starting daily PrEP.
  • For on-demand oral PrEP: Strict adherence to the 2-1-1 schedule is non-negotiable. Each dose plays a specific role in ensuring your protection.
  • For injectable PrEP: Maximum protection is reached 7 days after the first injection. You must then attend all your appointments (every 2 months) to maintain it.

What to do if you have trouble with adherence?

Maintaining a perfect routine can be challenging. If you frequently forget to take your medication, the important thing is to talk about it.

  • Discuss it with us: Your pharmacist is your ally. We can find practical solutions with you, such as reminder apps or pill organizers.
  • Consider an alternative: If missed doses are frequent, injectable PrEP might be a better option for you, as it completely eliminates this risk.

Your regular follow-up appointments are the ideal time to discuss your adherence to the treatment and adjust the strategy as needed. This is an essential dialogue for your safety.