What is the difference between PEP and PrEP?

This is an excellent question because even though the acronyms are similar, their roles are complete opposites.

The best way to see the difference is to compare the regular birth control pill to the morning-after pill.

PrEP: your planned, preventive protection

Think of PrEP as the "birth control pill" for HIV.

• Its role: It is a proactive protection that you take continuously before a potential exposure to HIV.
• How it's taken: On a regular basis (a daily pill or an injection every two months).
• Who it's for: For HIV-negative people who want continuous protection against HIV.

PEP (or PPE): your emergency solution after a risk

Think of PEP as the "morning-after pill" for HIV.

• Its role: It is an emergency treatment that is taken after a high-risk situation.
• How it's taken: It is a full 28-day course of treatment that must be started within a maximum of 72 hours after the risk.
• Who it's for: For HIV-negative people who have experienced a potential exposure and were not on PrEP.

In summary:

• PrEP = PRE-exposure. It is a continuous preventive strategy.
• PEP = POST-exposure. It is a one-time emergency treatment.